Research the Potential Benefits of PNC-28 Peptide (5mg Vial)
At DN Research, you can confidently buy PNC-28 peptide with the assurance of fast shipping, secure payment, and expert support every step of the way. Our commitment to quality and transparency ensures that you receive the highest-grade peptide for your research needs.
What is PNC-28 Peptide?
PNC-28 is a synthetic peptide designed to mimic the mdm-2-binding domain of the p53 protein. This peptide includes a penetratin sequence that enhances its ability to penetrate cancer cells. Unlike many other cancer-targeting peptides, PNC-28 primarily induces necrosis in cancer cells rather than apoptosis, leading to their rapid destruction while sparing normal cells.
PNC-28 has been a subject of extensive research due to its ability to selectively target malignant cells, particularly in aggressive forms of cancer. It has shown potential in pancreatic cancer research, demonstrating the ability to inhibit tumor growth and selectively eliminate cancer cells.
Benefits of PNC-28 Peptide
Scientific studies have explored several potential applications of PNC-28 peptide, including:
- selective cancer cell targeting without harming healthy cells
- potential inhibition of tumor growth and progression
- disruption of cancer cell membranes through necrosis
- novel therapeutic approach for aggressive and treatment-resistant cancers
PNC-28 as an Anti-Cancer Peptide
PNC-28 has shown significant promise in cancer research due to its ability to selectively induce necrosis in cancer cells. Unlike chemotherapy, which often damages both cancerous and healthy cells, PNC-28 targets malignant cells through its interaction with hdm-2, a protein overexpressed in many types of cancer. This interaction leads to the formation of membrane pores, disrupting the integrity of cancer cells and causing their destruction.
Preclinical research indicates that PNC-28 may:
- inhibit tumor growth in pancreatic cancer models
- selectively target cancerous tissues without affecting normal cells
- work independently of p53 mutations, which are common in many cancers
- induce necrosis, an alternative pathway to apoptosis for eliminating cancer cells
These findings suggest that PNC-28 could provide a new approach to cancer treatment, particularly for tumors resistant to traditional therapies.
PNC-28 and Tumor Suppression
PNC-28’s unique mechanism of action may offer benefits in tumor suppression. Research suggests that:
- PNC-28 binds to hdm-2 proteins found on cancer cells
- this binding disrupts cancer cell membranes, leading to necrosis
- PNC-28 does not affect normal, non-cancerous cells, reducing collateral damage
Because PNC-28 is independent of p53 status, it may have broad applications in treating various cancers, including pancreatic, lung, and colorectal malignancies.
PNC-28 and Cancer Cell Cytotoxicity
Studies suggest that PNC-28 exerts its cytotoxic effects by:
- creating pores in the membranes of cancer cells
- promoting rapid cancer cell death via necrosis
- showing efficacy in vitro and in vivo models of pancreatic cancer
These mechanisms make PNC-28 an attractive subject for further research in cancer therapy.
Buy PNC-28 Peptide (5mg Vial) at DN Research
For researchers exploring novel cancer-targeting peptides, PNC-28 presents a promising area of study. Visit DN Research today to secure your supply of this innovative peptide.
Legal Disclaimer
This product is sold as a pure compound for research purposes only and is not meant for use as a dietary supplement. Please refer to our terms and conditions prior to purchase.
Safety Information
Keep this product out of the reach of children. Limited research is available on its effects, and improper handling or consumption may lead to adverse effects. This product is intended for research use only and should only be handled by professionals with the proper knowledge and equipment. By purchasing this product, you agree to indemnify DN Research against any adverse effects resulting from misuse.
The information provided is for educational and research purposes only. This product is not a pharmaceutical or medication, and it has not been approved by the FDA for the treatment, prevention, or diagnosis of any disease or medical condition.
