SLU-PP-332 250mcg (60 Capsules)

Description

SLU-PP-332 is a synthetic small molecule designed as a potent agonist of estrogen-related receptors alpha, beta, and gamma (ERRα/β/γ), with the highest affinity for ERRα. This compound has attracted significant research attention due to its ability to mimic several physiological benefits of exercise, particularly through modulation of mitochondrial function and energy metabolism. By activating transcriptional programs linked to oxidative metabolism, SLU-PP-332 promotes mitochondrial biogenesis and fat oxidation, offering a promising avenue for research into metabolic health and obesity management.

Benefits of SLU-PP-332 in Metabolic Research

SLU-PP-332 has demonstrated multiple benefits in preclinical models that resemble the physiological changes induced by aerobic exercise. These include:

• Enhanced mitochondrial respiration and oxidative metabolism

• Increased endurance and physical performance in rodent treadmill studies

• Improved fatty acid oxidation and energy expenditure

• Reduction in fat mass without changes in food intake

• Improved insulin sensitivity in diet-induced obese mice

• Favorable shift toward oxidative type IIa muscle fibers

• Mimicking the effects of exercise at the cellular and systemic levels

These multifaceted actions make SLU-PP-332 a promising compound in the study of metabolic syndrome, obesity, and exercise mimetics.

SLU-PP-332 Dosage and Administration in Research

In experimental studies, SLU-PP-332 has been administered to rodent models at varying dosages, typically via oral gavage or intraperitoneal injection. These studies generally span two to four weeks, with daily administration leading to measurable changes in mitochondrial enzyme expression, energy metabolism, and body composition. While dosage can vary by study design and species, SLU-PP-332 is commonly used in the range of 5 to 20 mg/kg/day in mice. Researchers should carefully reference the specific protocols and pharmacokinetics for optimal experimental setup.

Indications and Research Applications

SLU-PP-332 is under active investigation for its potential in a variety of preclinical models. Research applications include:

• Investigating mitochondrial dysfunction in skeletal muscle

• Studying energy homeostasis and fat oxidation pathways

• Modeling metabolic disorders such as obesity and type 2 diabetes

• Exploring exercise mimetic compounds for sedentary or impaired populations

• Evaluating ERRα-mediated transcriptional activity

• Investigating oxidative fiber conversion in muscle physiology

Its utility spans research in endocrinology, exercise physiology, cellular metabolism, and pharmaceutical development.

SLU-PP-332 Side Effects and Safety Considerations

While SLU-PP-332 has shown a favorable safety profile in early rodent models, detailed toxicity and side effect profiles remain under investigation. Studies report no significant adverse effects at commonly used dosages. However, higher doses or long-term use require further study to determine their systemic impact. As a synthetic compound targeting nuclear receptors, it is essential to evaluate receptor specificity and potential off-target effects during experimental use.

Buy SLU-PP-332 at DN Research

Researchers exploring the intersection of exercise physiology, mitochondrial biology, and metabolic disease can find SLU-PP-332 to be a valuable research compound. At DN Research, we ensure that all compounds are rigorously tested for purity and are intended exclusively for qualified research professionals. Our SLU-PP-332 is available in secure, tamper-proof packaging and accompanied by all required documentation.

Visit DN Research today to explore our catalog and secure your supply of SLU-PP-332 for advanced metabolic and mitochondrial research.

Legal Disclaimer

This product is sold as a pure compound for research purposes only and is not meant for use as a dietary supplement. Please refer to our terms and conditions prior to purchase.

Safety Information: Keep this product out of the reach of children. This material has limited research available about it and may result in adverse effects if improperly handled or consumed. This product is not a dietary supplement, but a pure substance, sold as a raw material. We attest exclusively to the quality, purity, and description of the materials we provide. This product is for use and handling only by persons with the knowledge and equipment to safely handle this material. You agree to indemnify us for any adverse effects that may arise from improper handling and/or consumption of this product.

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