Description

Humanin 5MG Peptide Information

At DN Research, we offer high-purity Humanin peptide for research purposes. Humanin is a naturally occurring mitochondrial-derived peptide with significant neuroprotective, metabolic, and anti-aging properties. It has been widely studied for its potential in neurodegenerative diseases, cardiovascular protection, and metabolic health.

What is Humanin?

Humanin is a small mitochondrial-derived peptide consisting of 21 to 24 amino acids. It was first discovered in 2001 and has since been recognized for its ability to protect cells from various forms of stress and degeneration. Found in both the brain and other tissues, Humanin plays a critical role in cellular protection, particularly against oxidative stress, inflammation, and apoptosis (programmed cell death).

Research suggests that Humanin levels decline with age, which may contribute to age-related diseases, including Alzheimer’s, diabetes, and cardiovascular conditions. Studies indicate that increasing Humanin levels may enhance cellular resilience, making it a potential target for longevity and disease prevention research.

Humanin and Neuroprotection

Humanin has been extensively studied for its protective effects on neurons. It has shown potential in reducing cell death caused by toxic proteins associated with neurodegenerative disorders such as Alzheimer’s disease. Research suggests that Humanin may:

Inhibit amyloid-beta toxicity, a key driver of Alzheimer’s disease
Protect neurons from oxidative stress and apoptosis, preserving cognitive function
Activate cell survival pathways, including ERK1/2, AKT, and STAT3, which help prevent neuronal damage
Improve memory and cognitive function in aged animal models

Studies indicate that Humanin may slow neurodegeneration and enhance cognitive longevity, making it a promising peptide for brain health research.

Humanin and Inflammation & Oxidative Stress

Oxidative stress and inflammation are key contributors to aging and chronic diseases. Humanin has demonstrated strong antioxidant and anti-inflammatory effects, including:

Reducing reactive oxygen species (ROS) and oxidative damage
Lowering inflammatory cytokines, such as TNF-α and IL-6, in conditions like inflammatory bowel disease (IBD)
Protecting mitochondrial function, reducing cellular stress, and preventing inflammatory damage

These properties suggest that Humanin could be an important molecule in researching treatments for chronic inflammatory diseases and oxidative stress-related conditions.

Humanin and Metabolic Health

Humanin has been shown to play a role in regulating insulin sensitivity and glucose metabolism. Research has found that Humanin:

Enhances insulin sensitivity in the brain and peripheral tissues
Protects pancreatic beta cells, which are responsible for insulin production
Lowers blood glucose levels and improves glucose metabolism in diabetic models
Modulates metabolic pathways, making it a potential research candidate for obesity and type 2 diabetes treatments

These findings suggest that Humanin could be explored for its potential to improve metabolic health and insulin regulation.

Humanin and Cardiovascular Protection

Humanin has shown promise in protecting the heart and vascular system by:

Reducing cardiac stress and preventing heart muscle damage
Improving endothelial function, preserving blood vessel health
Lowering oxidative stress, reducing the risk of heart disease and atherosclerosis
Preventing apoptosis in heart cells, which may reduce damage from heart attacks

Humanin’s ability to improve cardiovascular function has led researchers to investigate its role in age-related heart diseases and longevity.

Humanin and Longevity Research

Studies on various organisms have linked higher Humanin levels to increased lifespan and healthspan. Research suggests that:

Higher Humanin levels correlate with longevity in humans, particularly in the offspring of centenarians
Humanin extends lifespan in animal models, such as C. elegans and rodents
Maintaining Humanin levels may slow age-related decline and protect against metabolic and neurodegenerative diseases

The growing interest in mitochondrial-derived peptides like Humanin highlights its potential role in longevity research and age-related disease prevention.

Legal Disclaimer

This product is sold as a pure compound for research purposes only and is not intended for human consumption. Please review our terms and conditions before purchase.

Safety Information

Keep this product out of the reach of children. This material is intended for laboratory research use only and should not be used for human ingestion, diagnosis, or treatment. Proper storage conditions should be maintained to ensure product integrity.

The information provided is for educational and research purposes only. The Food and Drug Administration (FDA) has not approved this compound for medical use, diagnosis, treatment, or disease prevention.

Humanin (5MG)