MK-677 12.5mg (60 Capsules)

Description

Ibutamoren, also known as MK-677, is an orally active, non-peptidic growth hormone secretagogue developed to stimulate the secretion of growth hormone (GH) and insulin-like growth factor 1 (IGF-1). It mimics the action of ghrelin by binding to the ghrelin receptor (GHSR) in the brain, leading to increased GH release. Unlike traditional GH therapy, MK-677 enhances the body’s own GH production, maintaining a physiological rhythm and offering a promising alternative for research into hormone regulation, muscle growth, and metabolic function.

Benefits of MK-677 (Ibutamoren)

Research suggests Ibutamoren may offer a range of physiological benefits through its action on the GH/IGF-1 axis:

• Supports lean muscle growth by increasing fat-free mass

• Improves sleep quality and REM sleep duration

• Enhances bone mineral density and skeletal strength

• Promotes skin regeneration and collagen synthesis

• Assists with fat metabolism without increasing visceral fat

• Contributes to overall recovery and physical regeneration

• May improve cognitive function through IGF-1 related neuroprotection

MK-677 Dosage and Administration

Ibutamoren is orally bioavailable, making it distinct among GH secretagogues. In research settings, it is typically administered once daily due to its long half-life. Dosage can vary depending on the application and study parameters, but studies often use 10 to 25 mg per day.

Long-term administration has been shown to maintain elevated GH and IGF-1 levels, mimicking youthful endocrine profiles. Oral delivery eliminates the need for injections, contributing to its interest in both clinical and experimental settings.

Indications and Research Applications

MK-677 has been explored in both animal and human studies for a variety of research purposes, including:

• Growth hormone deficiency

• Sarcopenia and age-related muscle wasting

• Osteoporosis and reduced bone density

• Sleep disorders, particularly those related to GH deficiency

• Fatty liver disease and metabolic dysregulation

• Cognitive decline and neurodegenerative conditions

Clinical trials have demonstrated significant improvements in body composition, GH profile, and markers of bone formation. Its effect on sleep and neurocognition is currently being explored for additional therapeutic insights.

Potential Side Effects

Although MK-677 is generally well-tolerated in research settings, reported side effects include mild water retention, increased appetite, transient insulin resistance, and muscle aches. These effects appear to be dose-dependent and reversible upon discontinuation.

Long-term human data remains limited, and further investigation is needed to assess potential risks with extended use, particularly in populations with metabolic or endocrine imbalances.

Buy Ibutamoren (MK-677) at DN Research

At DN Research, Ibutamoren (MK-677) is available as a high-purity research compound (99%+), suitable for advanced study in hormone regulation, metabolic support, and muscle physiology. All compounds are independently verified for purity and integrity through rigorous testing.

Whether you are conducting studies on muscle development, aging, sleep, or bone health, MK-677 offers a unique oral solution for stimulating the GH/IGF-1 axis.

Legal Disclaimer

This product is sold as a pure compound for research purposes only and is not intended for use as a dietary supplement. Please refer to our terms and conditions prior to purchase.

Safety Information: Keep this product out of reach of children. This material has limited research available about it and may result in adverse effects if improperly handled or consumed. This product is not a dietary supplement, but a pure substance sold as a raw material. We attest exclusively to the quality, purity, and description of the materials we provide. This product is intended for handling and use only by qualified individuals with the proper knowledge and equipment. By purchasing this product, you agree to indemnify us for any adverse effects resulting from misuse or mishandling.

The articles and information presented on this website are intended solely for educational and research purposes. These products are not pharmaceuticals or medications, and have not been approved by the Food and Drug Administration for the treatment, diagnosis, or prevention of any disease or condition.