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N-Acetyl Semax (20mg)

50.00

N-Acetyl Semax Amidate is a potent nootropic peptide with enhanced stability and bioavailability, studied for its cognitive, neuroprotective, and anxiolytic effects.

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Description

N-acetyl semax amidate is a synthetic heptapeptide based on the adrenocorticotropic hormone (ACTH 4–10) fragment, modified to enhance its potency, stability, and duration of action. This version includes both N-terminal acetylation and C-terminal amidation, which contribute to superior blood-brain barrier penetration and resistance to enzymatic degradation. As a neuropeptide compound, it is widely researched for its cognitive-enhancing, neuroprotective, and anxiolytic properties.

Its stability in lyophilized form ensures a longer shelf life and preservation of peptide integrity, making it suitable for use in advanced neurocognitive and neurological research settings.

Benefits of n-acetyl semax amidate peptide

Scientific literature has explored a variety of potential applications for this compound, including:

  • enhancement of cognitive function and focus

  • improved learning and memory retention

  • protection against ischemic brain injury

  • reduction of stress and anxiety-related behaviors

  • modulation of mood and neurochemical balance

  • improvement in motivation and mental energy

These effects make it a candidate of interest in research on cognitive decline, neuroplasticity, and neuropsychiatric disorders.

N-acetyl semax amidate and neuroprotection

Studies in animal models have shown that n-acetyl semax amidate has notable neuroprotective properties, particularly in contexts involving cerebral ischemia and oxidative stress. It has been found to modulate the expression of key genes involved in the inflammatory response and neurotransmission. Research also indicates that this peptide can support neuronal recovery and synaptic integrity following hypoxic or ischemic events.

In rat models of chronic brain ischemia, administration of semax analogs contributed to improvements in muscle activity, motor coordination, and emotional regulation, all of which suggest restoration of central nervous system function.

N-acetyl semax amidate and cognitive function

This compound has shown potential to support learning capacity and mental performance. Studies suggest it interacts with neurotrophic factors such as brain-derived neurotrophic factor (BDNF) and may stimulate mechanisms involved in synaptic plasticity. In rodent research, semax analogs have been linked to increased expression of neuroprotective and neurotransmitter-regulating proteins in brain regions associated with memory and attention.

In one study, semax was found to prevent memory impairment in rats exposed to hypoxia, as measured by object recognition tasks. These findings indicate its value for further exploration in the context of cognitive decline and memory preservation.

Indications and research applications

N-acetyl semax amidate is under active investigation for a variety of applications, including:

  • stroke and post-ischemic recovery

  • age-related cognitive decline

  • chronic fatigue and mental burnout

  • stress-induced neurological dysfunction

  • neuroinflammation and oxidative damage

Its unique structure and enhanced bioactivity make it particularly suited for researchers focused on brain resilience, nootropics, and neuroregeneration.

Buy n-acetyl semax amidate at DN Research

DN Research supplies high-purity, lyophilized n-acetyl semax amidate in sterile vials, ready for reconstitution under laboratory conditions. Each 20mg vial is verified for purity via HPLC analysis and packaged to maintain stability during storage and transport. This formulation is intended for professional research use only.

Legal disclaimer

This product is sold as a pure compound for research purposes only and is not intended for use as a dietary supplement. Please refer to our terms and conditions prior to purchase.

Safety information: Keep this product out of the reach of children. This material has limited research available and may result in adverse effects if improperly handled or consumed. This product is not a dietary supplement, but a pure substance, sold as a raw material. We attest exclusively to the quality, purity, and description of the materials we provide. This product is for use and handling only by persons with the knowledge and equipment to safely manage this material. You agree to indemnify DN Research for any adverse effects that may result from improper handling and/or consumption.

The articles and information on products found on this website are provided exclusively for educational and research purposes. These items are not pharmaceuticals or medications, and the Food and Drug Administration has not approved them for the treatment or prevention of any disease or medical condition.