Thymosin Beta 4 Fragment 1-4 (10mg) 98.5%
Molecular Information
- Molecular Formula: C16H26N4O4
- Molecular Weight: 338.41 g/mol
- Synonyms: TB4 Active Fragment, Thymosin Beta-4 (1-4) Peptide
Research Applications
- Immune system modulation
- Tissue regeneration and wound healing
- Anti-inflammatory properties
- Cellular growth and repair
What is Thymosin Beta-4 Active Fragment?
Thymosin Beta-4 (TB4) is a naturally occurring peptide known for its role in cell migration, tissue repair, and immune function. It plays a crucial role in the regulation of actin, a protein essential for cell movement and structure. The Thymosin Beta-4 Fragment 1-4 is a bioactive sequence derived from the larger TB4 molecule, representing the first four amino acids of the peptide. Despite its smaller size, this fragment retains many of the biological properties of full-length TB4, including its impact on immune response, inflammation, and wound healing.
Thymosin Beta-4 and Immune System Modulation
TB4 has been widely studied for its ability to influence immune system activity. Research suggests that it can regulate inflammatory responses by modulating key mediators such as NLRP3 inflammasome, an important protein complex involved in immune system activation. Studies indicate that TB4 plays a role in suppressing excessive immune activation, which may be useful in treating inflammatory diseases and conditions such as liver fibrosis.
Additionally, TB4 has been observed to regulate immune responses during viral infections, showing potential for modulating both innate and adaptive immunity.
Healing and Tissue Regeneration
TB4 is well-documented for its regenerative properties, particularly in wound healing and tissue repair. It promotes the migration of cells essential for tissue regeneration, including fibroblasts and keratinocytes. Research has shown that TB4 is effective in corneal wound healing, where it aids in restoring damaged ocular surfaces and maintaining corneal health.
Moreover, TB4 has been implicated in organ repair, particularly in the liver. Studies have demonstrated its ability to enhance liver regeneration following viral infections and promote overall organ recovery.
Anti-Inflammatory Properties
TB4 exhibits strong anti-inflammatory effects, making it a potential research candidate for conditions involving excessive inflammation. Studies suggest that it can:
- Protect neuronal cells from toxicity by balancing neurotrophic factors and receptors.
- Suppress inflammatory responses in periodontal ligament cells, which may be relevant to dental and bone health.
- Inhibit osteoclastic differentiation, a process involved in bone degradation, indicating potential applications in bone health and repair.
Legal Disclaimer
This product is sold as a pure compound for research purposes only and is not meant for use as a dietary supplement. Please refer to our terms and conditions prior to purchase.
Safety Information
Keep this product out of the reach of children. Limited research is available on Thymosin Beta-4 Fragment 1-4, and improper handling may result in unintended effects. This peptide is not a dietary supplement and is intended solely for laboratory research.
We ensure the quality and description of all products but are not responsible for improper usage.
The content provided on this website is for informational and educational purposes only. This peptide has not been evaluated by the FDA and is not intended for diagnosing, preventing, or treating any medical condition.
